Yeast metabolically engineered to synthesize precursors of powerful anti-cancer drug vinblastine [Registered]

The chemical synthesis of the potent anticancer drug Vinblastine poses significant challenges owing to its complex three-dimensional structure. Vinblastine is a heterodimer of the chemical compounds catharanthine and vindoline, and currently available methods for the mass production of vinblastine are both costly and unsustainable.… Login to continue