International Sugar Journal

The potential of synthetic biology expanded to produce chemicals not found in nature [Full subscriber]

Researchers at Berkeley Lab and UC Berkeley have engineered the microbe E. coli to produce a molecule that, until now, could only be synthesized in a laboratory.

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Givaudan partners with Ginkgo Bioworks to produce biobased ingredients for the flavours and fragrances sectors [Full subscriber]

The Swiss flavour and fragrance giant Givaudan is partnering with synthetic biology platform company Ginkgo Bioworks to develop a new series of biobased ingredients.

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Conagen scales up production of biobased capsaicinoid compounds [Full subscriber]

The biotech start-up Conagen recently announced it has successfully scaled up its fermentation process for the production of premium capsaicin and its related capsaicinoid molecules such as dihydrocapsaicin and nonivamide, a capsaicinoid used in topical muscle pain relievers and in synthetic pepper spray.

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Naturally sourced cyan blue could replace synthetic blue dye used in the food industry [Full subscriber]

an international team of researchers, leveraging synthetic biology and computational protein design tools, have developed a long-sought naturally derived cyan blue colourant sourced from red cabbage anthocyanin pigments that may offer an alternative to the synthetically-produced industry standard blue dye, although more testing is needed to determine the compound’s safety.

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Extending enzymes lifespan through metabolic engineering would drive productivity [Full subscriber]

The continuous replacement of enzymes and other proteins appropriates up to half the maintenance energy budget in microorganisms and plants. High enzyme replacement rates, therefore, cut the productivity of biosystems ranging from microbial fermentation to crops. Enzyme engineering via synthetic biology to extend its life is proposed by researchers from the University of Florida, Argonne National Laboratory, The University of Chicago and the University of Western, whereby they also present a new benchmark for evaluating the durability of any enzyme.

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New synthetic biology tools paves way for complex plant engineering [Full subscriber]

Agricultural biotechnology strategies often require the precise regulation of multiple genes to effectively modify complex plant traits. However, most efforts are hindered by a lack of characterized tools that allow for reliable and targeted expression of transgenes. Now, researchers at Joint BioEnergy Institute (JBEI) in the USA have developed a new set of synthetic biology tools that could unlock advanced plant engineering.

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Speeding up metabolic engineering with machine learning [Full subscriber]

Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules such as renewable biofuels or anticancer drugs. However, traditional synthetic biology approaches involve ad-hoc engineering practices, which lead to long development times. Now, researchers at the Department of Energy’s Lawrence Berkeley National Laboratory have created a new tool that adapts machine learning algorithms to the needs of synthetic biology, dramatically reducing the time spent engineering drugs and chemicals.

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Bioengineered microbes facilitate the production of isoprenoids [Full subscriber]

Now, researchers at the University of South Florida have engineered microorganisms for synthesizing isoprenoids.

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E. coli engineered to synthesise terpenes [Registered]

Researchers from North Carolina State University have developed an artificial enzymatic pathway for synthesizing isoprenoids, or terpenes, in bioengineered E. coli.

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Rewiring plant defence genes to resist disease attack [Registered]

Plants can be genetically rewired to resist the devastating effects of disease – significantly reducing crop waste worldwide – according to new research into synthetic biology.

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