International Sugar Journal

E. coli engineered to fully exploit cellulosic sugars to produce muconic acid [Full subscriber]

researchers at Kobe University, Japan have developed .a new strategy called Parallel Metabolic Pathway Engineering (PMPE), allowing them to fully exploit both sugars for target chemical production and microbe propagation. They used this approach to alter E. coli bacteria in order to successfully boost the production of the nylon precursor muconic acid.

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Redesigning a bacterial enzyme aids production of rare sugar from table sugar [Registered]

Researchers from the Ghent University, Belgium have modified sucrose phosphorylase from Bifidobacterium adolescentis (BaSP) that can be used as a transglucosylase in the production of rare sugar nigerose from sucrose and glucose. This could provide a cheap and convenient route to make enough nigerose to explore potential applications in the food and pharmaceutical industries.

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Advances in synthetic biochemistry could lead to production of biobased chemicals from glucose [Registered]

Bowie and his team created a promising method as an alternative, which he refers to as synthetic biochemistry, that bypasses the requirement for cells.

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Johnson Matthey and Rennovia commence production of glucaric acid at its new mini-plant [Registered]

In March 2014, both companies announced their collaboration to develop and commercialize production technology for biobased glucaric acid and adipic acid. Under the collaboration, Rennovia and JM Davy will work together to develop and demonstrate the processes based on Rennovia’s technology for the catalytic aerobic oxidation of glucose to glucaric acid, as well as the catalytic hydrogenation of glucaric acid to adipic acid. The goal of the collaboration is to develop and jointly license a technology package enabling commercial production of these chemical products.

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