International Sugar Journal

Combination of eutectic solvents and genetic engineering advances cellulosic biofuels production [Registered]

the international team of researchers led by The Korea Institute of Science and Technology (KIST) have developed a process that leverages the genetic engineering of lignin and bio-derived deep eutectic solvents (DESs).

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Competitive isobutanol production process using supercritical carbon dioxide as solvent [Registered]

Researchers at Worcester Polytechnic Institute (WPI) in Worcester, Massachusetts have developed a novel process using an unorthodox solvent and engineered microbe to produce isobutanol economically.

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A new combinatorial one-step metabolic engineering [Registered]

In the production of chemicals and biofuels via the microbial route, designing an optimal microbial cell factory often requires overexpression, knock-down, and knock-out of multiple gene targets. Unfortunately, such rewiring of cellular metabolism is often carried out sequentially and with low throughput.

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Researchers modify both E. coli and tobacco plant to speed up production of muconic acid from lignin [Registered]

Researcher US’ Sandia National Laboratories have developed a novel process to produce from lignin muconic acid and pyrogallol which currently have a combined market value of US$255.7 billion.

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Artemisia annua genetically engineered to double artemisinin production [Registered]

An international research team led by the Center for Research in Agricultural Genomics (CRAG) and Sequentia Biotech S.L. has genetically engineered the plant Artemisia annua to produce twice as much artemisinin.

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Producing drug from plant and then from yeast [Registered]

Researchers at Stanford University have isolated the machinery for making a common cancer-fighting drug from an endangered plant. They then put that machinery into a common, easily grown laboratory plant, which was able to produce the chemical. The technique could potentially be applied to other plants and drugs, creating a less expensive and more stable source for those drugs.

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Systems metabolic engineering strategies outlined to produce substitute petrochemicals [Registered]

Thanks to advances in genetic engineering and our knowledge of cellular metabolism, conventional metabolic engineering efforts have succeeded to a certain extent in developing microbial strains that overproduce bioproducts at an industrial level. However, many metabolic engineering projects launched in academic labs do not reach commercial markets due to a failure to fully integrate industrial bioprocesses.

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