News International Sugar Journal

Structural analysis of an enzyme synthesizing bisabolene reveals an effective advanced biofuel production route [Registered]

Bisabolane, a member of the terpene class of chemical compounds used in fragrances and flavorings, holds high promise as a biosynthetic alternative to D2 diesel fuel. A team of researchers with the U.S Department of Energy’s Joint BioEnergy Institute (JBEI) has determined the three-dimensional crystal structure of a protein that is key to boosting the microbial-based production of bisabolane as an advanced biofuel. The JBEI research team, led by bioengineers Paul Adams and Jay Keasling, determined the protein crystal structure of an enzyme in the Grand fir (Abies grandis) that synthesizes bisabolene, the immediate terpene precursor to bisabolane. The performance…

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