News International Sugar Journal

Researchers solve century-old chemistry problem that will streamline synthesis of certain compounds [Registered]

Chemists at The Scripps Research Institute (TSRI) have found a way to apply a “foundational reaction” of organic chemistry to a stubborn class of chemicals, in a transformation that has been thought impossible for a century. The classic SN2 reaction has enabled chemists to build and modify many pharmaceuticals as well as other useful organic molecules. While the reaction had been thought to exclude certain compounds, a paper in the September 12, 2013 issue of the journal Nature describes a new SN2-like reaction that overcomes this limitation. “We’ve widened the range of molecules that are responsive to this foundational technique;…

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