News International Sugar Journal

Metabolically engineered E. coli produces phenol from glucose [Registered]

Phenol is an important commodity chemical, and is a starting material for the production of numerous industrial chemicals and polymers, including bisphenol A and phenolic resins, and others. At present, the production of phenol entirely depends on the chemical synthesis from benzene, and its annual production exceeds 8 million tons worldwide. Microbial production of phenol seems to be a non-viable process considering the high toxicity of phenol to the cell. Researchers at the Korea Advanced Institute of Science and Technology (KAIST) have reported the successful development of an engineered Escherichia coli strain which can produce phenol from glucose. E. coli…

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