News International Sugar Journal

E. coli bioengineered to produce high levels of D-Ribose [Registered]

Researchers at the University of Toronto, Canada, describe the metabolic engineering strategy they used to increase the yield of D-ribose from the genetically modified E. coli, which were able to produce D-ribose from mixtures of glucose and xylose. The paper, by Pratish Gawand and Radhakrishnan Mahadevan, is published online in the journal Industrial Biotechnology. D-ribose is a naturally produced pentose sugar with several commercial applications. It is used as a sweetener, as well as a starting compound for synthesis of riboflavin, inosine monophosphate, and several antiviral drugs. D-ribose is also used as a nutritional supplement for muscle recovery among athletes,…

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