International Sugar Journal

Extending enzymes lifespan through metabolic engineering would drive productivity [Full subscriber]

The continuous replacement of enzymes and other proteins appropriates up to half the maintenance energy budget in microorganisms and plants. High enzyme replacement rates, therefore, cut the productivity of biosystems ranging from microbial fermentation to crops. Enzyme engineering via synthetic biology to extend its life is proposed by researchers from the University of Florida, Argonne National Laboratory, The University of Chicago and the University of Western, whereby they also present a new benchmark for evaluating the durability of any enzyme.

Read more …